Severe/non localized (may affect the entire body); can include but is not limited to: abdominal cramping or pain, pain or tightness in the chest, diarrhea, difficulty swallowing, dizziness, fear or anxiety, flushing of the face, nausea or vomiting, heart palpitations, swelling of the face, eyes, or tongue, weakness, wheezing, difficulty breathing, unconsciousness, other.